With your IP preheating to Saute, roughly chop onion and celery. season chuck roast with 1 tsp of salt and pepper and flour.
Brown chuck roast in the IP until brown on both side, remove chuck roast cubes and deglaze Instant Pot with dark beer.
Add chuck back into Instant pot along with beef stock, veggies, potatoes and seasonings.
Close lid and set to pressure cook for 25 minutes. Allow another 5-10 minutes for pressure to release
Notes
For a thicker stew, add a corn starch slurry of 1 tbsp corn starch slurry to 2 tbsp cold water, and stir into Instant Pot after steam has been released.